On this tour of the universe of signs, Jesper Hoffmeyer travels back to the Big Bang, visits the tiniest places deep within cells, and ends his journey with us - complex organisms capable of speech and reason. He shows that life at its most basic depends on the survival of messages written in the code of DNA molecules, and on the tiny cell - the fertilized egg - that must interpret the message and from it construct an organism. What propels this journey is Hoffmeyer's attempt to discover how nature could come to mean something to someone; indeed, how "something" could become "someone." How could a biological self become a semiotic self?